Rapid small molecules detection using our aptamer-based displacement approach

The challenge
Small molecules such as antibiotics, drugs, toxins and food additives are often perceived as difficult targets to obtain a suitable affinity ligand. The development of rapid, cost-effective, single-step assays for the sensitive and specific detection of small molecules are very attractive for many applications ranging from life sciences to environmental analysis. Unfortunately, current […]

Aptamers show high specificity for closely related proteins with single point mutations

13th August 2019
Under pathophysiological conditions, transcription of proteins can lead to changes in amino acid structure known as that can either destroy their activity or impart them with new functionality. These transformations can be indicators of disease occurrence or progression and therefore point mutations on proteins can serve as useful biomarkers for disease. However, their […]