Aptamer Applications: Biosensors part 1

4th July

Aptamers are increasingly being used in Biosensors. Biosensors are devices that use biological molecules, especially enzymes or antibodies, or living organisms to detect the presence of an analyte. By modifying an aptamer with an appropriate reporter group, we are able to develop biosensors that measure analytes qualitatively and/or quantitatively.

Modes in which aptamers are utilised […]

Aptamer Applications: ELONA

27th June, 2017
An application that we have proven to be successful for aptamers is Enzyme-Linked Oligonucleotide Assays (ELONA). These are similar to ELISA but utilise the benefits that aptamers offer.

ELONA use aptamers in two ways; to capture the target molecule on the plate and for use as a detection molecule. After the sample is immobilised […]

  • 2 aptamers binding to small molecule targets and one aptamer binding to a large molecule target

What is an aptamer?

10th May 2017
AptaBasics:  ‘What is an Aptamer’?

An aptamer is a sequence of single strand nucleic acid (DNA or RNA) with a variable region of about 40 nucleotide bases. This variable sequence confers each aptamer with a unique 3 dimensional structure and potential ligand binding capability.  These factors make aptamers high affinity and specific binding molecules, […]

The New Age of Aptamer Based Biosensors

29 July 2016

There is an increasing interest in developing new biosensors for diagnostics and basic research applications. In light of the emerging aptamer technology, aptamer-based biosensors (Aptasensors) are expected to be one of the most promising devices in bioassay related applications (Han, Liang, and Zhou., 2010). However given this noted promise, the application of aptamer […]